Journal: Journal of Diabetes Science and Technology

Article Title: Artificial Pancreas Device Systems for the Closed-Loop Control of Type 1 Diabetes

doi: 10.1177/1932296815617968

Figure Lengend Snippet: Summary of the Closed-Loop Artificial Pancreas Device (APD) Systems Identified.

Article Snippet: 5 , Diabetes Assistant (DiAs); including inControl (brand name) , TypeZero Technologies LLC (licensee); international research teams: USA (Sansum Research Institute, Santa Barbara, California, Universities of Virginia and Stanford), France (Montpellier), Netherlands (Amsterdam), Israel (Petah Tikva) and Italy (Padova) , DiAs is a modular artificial pancreas platform based on an Android smartphone. The smartphone app contains the computer program that controls blood glucose (including predicting when levels will rise and fall). It wirelessly receives data from the CGM (Dexcom G4) and gives commands via Bluetooth to an insulin pump (eg, Tandem t:slim or Accu-Check from Roche). There is also a special Bluetooth box that connects to local data servers and the Cloud. The controller is compatible with any CGM or insulin pump. The system is being tested in long-term (1-3 months) clinical trials in the home setting. TypeZero has developed a smartphone-based APD called inControl, a mobile-based advisory system called inControl Advice that generates real-time recommendations for meals, basal rates, bolus calculations and exercise decisions, and a cloud-based analytics and support system called inControl Cloud (which enables real-time monitoring and notifications for caregivers, and retrospective analysis of data). Intended use: daytime, night time, during exercise; children and adult. Recent published research. - Ongoing and planned research (including the use of the ZMPC algorithm on the DiAs platform): NCT02463682, NCT02514785, NCT02506764, NCT02302963. Further information: http://www.medpagetoday.com/Blogs/DiabetesDiscovery/51124 ; http://typezero.com/ ; http://www.healthline.com/diabetesmine/typezero-tech-closed-loop-commercialization#1 .

Techniques: Software

Journal: Journal of Diabetes Science and Technology

Article Title: Artificial Pancreas Device Systems for the Closed-Loop Control of Type 1 Diabetes

doi: 10.1177/1932296815617968

Figure Lengend Snippet: Further Information on the Closed-Loop Artificial Pancreas Device (APD) Systems Identified

Article Snippet: 5 , Diabetes Assistant (DiAs); including inControl (brand name) , TypeZero Technologies LLC (licensee); international research teams: USA (Sansum Research Institute, Santa Barbara, California, Universities of Virginia and Stanford), France (Montpellier), Netherlands (Amsterdam), Israel (Petah Tikva) and Italy (Padova) , DiAs is a modular artificial pancreas platform based on an Android smartphone. The smartphone app contains the computer program that controls blood glucose (including predicting when levels will rise and fall). It wirelessly receives data from the CGM (Dexcom G4) and gives commands via Bluetooth to an insulin pump (eg, Tandem t:slim or Accu-Check from Roche). There is also a special Bluetooth box that connects to local data servers and the Cloud. The controller is compatible with any CGM or insulin pump. The system is being tested in long-term (1-3 months) clinical trials in the home setting. TypeZero has developed a smartphone-based APD called inControl, a mobile-based advisory system called inControl Advice that generates real-time recommendations for meals, basal rates, bolus calculations and exercise decisions, and a cloud-based analytics and support system called inControl Cloud (which enables real-time monitoring and notifications for caregivers, and retrospective analysis of data). Intended use: daytime, night time, during exercise; children and adult. Recent published research. - Ongoing and planned research (including the use of the ZMPC algorithm on the DiAs platform): NCT02463682, NCT02514785, NCT02506764, NCT02302963. Further information: http://www.medpagetoday.com/Blogs/DiabetesDiscovery/51124 ; http://typezero.com/ ; http://www.healthline.com/diabetesmine/typezero-tech-closed-loop-commercialization#1 .

Techniques: Modification, Injection, Concentration Assay, Software, MicroChIP Assay, Sampling, Activity Assay